To clarify their roles, we assessed the association of genetically predicted liver enzymes (ALT, ALP and GGT) with ischemic heart disease (IHD) using large extensively genotyped case-control studies of coronary artery disease (CAD)/myocardial infarction (MI) and T2DM12, 13, 14, 15. Here, GPT is linked to myocardial infarction.