PRKAR1A and cancer: Analysis of a clinical patient database, the cancer genome atlas (TCGA), by cBioPortal (http://www.cbioportal.org/public-portal/), demonstrated a weak positive correlation between PRKAR1A mRNA expression and CDH1 mRNA (encoding E-cadherin protein) level in 522 lung adenocarcinoma patients (r = 0.1285; P = 0.0033; Fig. 4A).