In fact, just four female carriers suffered from bilateral myopic chorioretinal degenerations but all of them were heterozygous for ORF15-c.2091_2092insA, indicating that PM could represent the phenotypic expression of RP-related mutant heterozygosities located in various exons of RPGR gene, as previously observed in several pedigrees of both Asian and Caucasian descents20, 21, 22, 23, 24, 25, 26, 27, 28. The gene discussed is RPGR; the disease is Chorioretinal atrophy.