The findings probably partially explained Schiopu's 7 reports that oxLDL antibody treatment had a regression effect on high‐fat diet‐induced atherosclerosis in Apobec‐1−/−/LDLR−/− mice, and inhibitory effect on monocyte MCP‐1 release and inflammatory cell infiltration to the plaque area. This evidence concerns the gene APOBEC1 and atherosclerosis.