Fig. 1, Fig. 2 indicate blood glucose levels, body weight, and testis weight and sperm parameters. Fig. 3, Fig. 4 are a visual evidence for the changes due to diabetes and Resveratrol in expression of PARP1 in Leydig cells and in intra-testicular blood vessel smooth muscle cells. Fig. 5, Fig. 6 present data supporting the seminiferous epithelial stage-dependent expression of PARP1 and stage-independent expression of SirT1 in the testis. This evidence concerns the gene SIRT1 and diabetes mellitus.