Alternatively, peptidic inhibitors with the ability of fusing to the translocation domain and inhibiting the pVHL/HIF-1α interaction have been demonstrated to stabilize HIF-1α, confirming the idea that inhibition of pVHL/HIF-1α interaction can be applied as an alternative or complementary way with PHD inhibitors for the treatment of anemia (Harten, Ashcroft & Maxwell, 2010). The gene discussed is VHL; the disease is anemia (phenotype).