When we analyzed the composition of cells after immunization with the various vaccines, we detected significant differences in the frequency of myeloid cell populations in the spleens and BM of tumor-inoculated mice treated with a licofelone-containing vaccine with the levels of Gr-1+ CD11b+ IMCs and Gr-1− F4/80+ macrophages being decreased. The gene discussed is ITGAM; the disease is neoplasm.