HDAC9 and colonic neoplasm: The supernatant of human fecal slurry and pectin has been reported to have potent HDAC in inhibitory effects on colon cancer, due to production of butyrate (Waldecker et al., 2008) but the epigenetic effect of butyrate varies with type of dietary lipid intake and more pronounced effect was observed with fish oil compared with corn oil (Crim et al., 2008).