We selected JAK3, Ras-specific guanine nucleotide-releasing factor 1 (RASGRF1), carboxypeptidase X (CPXM1), and Src homology 2 domain-containing adapter protein F (SHF) as the common BC markers, Dynamin 3 (DNM3), Caveolin 2 (CAV2), Homeobox protein Hox-A10 (HOXA10), and B3GNT5 as the luminal-dominant markers, and ST3GAL6, Dachshund homolog 1 (DACH1), P2X purinoceptor 3 (P2RX3), and chr8:23572595 as the TN-dominant markers (Table 2, Additional file 2: Tables S4 and S5). The gene discussed is SHF; the disease is breast cancer.