To determine the association between senescent-myofibroblasts or TGF-β-myofibroblasts and gene expression in human tumors we applied weighted gene co-expression network analysis (WGCNA) to the Cancer Genome Atlas HNSCC RNA-sequencing dataset (TCGA Network, 2015) [35]. This evidence concerns the gene TGFB1 and head and neck squamous cell carcinoma.