Kc demonstrated the highest release of VEGF in both normoglycemia (553 ± 6 pg/ml vs. 172 ± 13 pg/ml and 127 ±62 pg/ml for Kc vs. ASC and DF, respectively, p<0.001) and hyperglycemia (552 ± 8 pg/ml vs. 122 ± 66 pg/ml and 35 ± 10 pg/ml for Kc vs. ASC and DF, respectively, p<0.001). The gene discussed is VEGFA; the disease is Hyperglycemia.