ALB and diabetes mellitus: Based on the subgroup analysis of 4D, it may be possible to recommend that statins treatment be initiated if LDL-C is higher than 145 mg/dl in hemodialysis patients.[23] However, Kim et al demonstrated that high serum LDL-C (≥100mg/dl) at the time of HD commencement was a significant independent risk factor for the composite outcome of all-cause mortality and CV events in 867 incident HD patients during the early stages of dialysis, even after adjusting for age, gender, diabetes mellitus, preexisting CV disease, albumin, and hs-CRP.