With respect to the analysis of the influence of the 57 analyzed SNPs on the DFS, the results showed a robust association for rs8086 and rs522951 (Table 3; Fig 1) between DFS of the patients and genotype for these polymorphisms within ACSL1 and SCD respectively, genes that codify for two enzymes that have been recently described as a LM driving-force in colon cancer progression [10]. This evidence concerns the gene ACSL1 and malignant colon neoplasm.