Diabetes mellitus (DM) is characterized by hyperglycemia resulting from defects in insulin secretion and/or insulin resistance in target tissues.[1] The current classification of DM is primarily based on etiology and includes type 1 DM (T1DM), type 2 DM (T2DM), gestational diabetes, and other types of DM. This evidence concerns the gene INS and type 2 diabetes mellitus.