Based on quantitative real-time reverse transcription PCR (qRT-PCR) analysis of the treated cells, levels of MICA, MICB, Nectin-2, and PVR mRNA were significantly greater in MM cells incubated with 10 nM bortezomib compared to those in control MM cells (0 nM) (Figure 2D). The gene discussed is MICB; the disease is Miyoshi myopathy.