MSTN and hyperinsulinemic hypoglycemia, familial, 4: To clarify the role of these miRNAs in skeletal muscle hypertrophy induced by myostatin deficiency, we transfected miRNA mimics (miR-127, miR-300, miR-329, miR-337-3p, miR-376a, miR-379, miR-381, miR-411, miR-434-5p, and miR-540-3p) into C2C12 myotubes and measured the myotube diameter.