Meanwhile, a poor prognosis in NSCLC was found in the increased levels of PVT1 and MALAT1 (PVT1: HR = 3.05, 95% CI = 2.15-4.34, P < 0.001, fixed-effect) (MALAT1: HR = 1.66, 95% CI = 1.04-2.63, P = 0.03, fixed-effect) (Figure 3B-3C). This evidence concerns the gene PVT1 and non-small cell lung carcinoma.