Thus, to find out whether Gankyrin was associated with poor prognosis of NSCLC patients through promoting tumor metastasis, we applied lenti-virus transduction to knockdown the Gankyrin expression in Calu-1 and H838 cell lines (Figure 2A and 2B) and then detected the migratory and invasive ability of these cell lines, in which the Gankyrin expression was relatively higher than that in other NSCLC cell lines. Here, PSMD10 is linked to non-small cell lung carcinoma.