ID1, a transcriptional regulator that cooperates with oncogenic Ras in the development of metastatic breast cancer, was also upregulated in relapsed NRI AMLs.32 Similar to flow cytometric and RPPA analyses, several mediators of apoptosis were differentially expressed between de novo NRD and relapsed NRI AMLs (Supplementary Figure S3). This evidence concerns the gene ID1 and breast carcinoma.