Further evidence, implicating the HMGA1 locus as one conferring high risk for the development of type 2 diabetes, has been provided recently by showing that a specific single-nucleotide insertion at position −13 of exon 6 of the HMGA1 gene (IVS5–13insC; more precisely, c.136–14_136–13insC; rs139876191), significantly associates with type 2 diabetes in a transethnic meta-analysis17. The gene discussed is HMGA1; the disease is type 2 diabetes mellitus.