High circulating Angpt2 level was still significantly associated with LVH in CKD patients with hsCRP ≦ 1 mg/L (P-trend = 0.02) and those with eGFR ≧ 20 ml/min/1.73 m2 (P-trend = 0.007) after adjustment of age and sex, but not in those with hsCRP >1 mg/L and those with eGFR < 20 ml/min/1.73 m2. The gene discussed is ANGPT2; the disease is chronic kidney disease.