CXCL13 and lobular neoplasia: Thus, we speculated that an abnormally increased serum CXCL13 level could induce excessive chemotaxis of B cells, T cells, and dendritic cells into renal tissues of LN and subsequent excessive ELT formation, which promotes a vicious cycle of the expansion and perpetuation of inflammatory cell aggregates resulting in persistence and chronicity of the renal inflammation in LN patients.