Moreover, serum CXCL13 levels were positively correlated with SLEDAI, the degree of B-cell infiltration in renal tissue, and AI but were negatively correlated with the C3 level, suggesting a possible correlation between abnormally increased serum CXCL13 levels and ELT formation and renal impairment in LN patients. Here, CXCL13 is linked to lobular neoplasia.