AKT1 and neoplasm: The property of hnRNPA2 as a KAT is similar to other transcriptional coactivators thatremodel chromatin DNA by histone acetylation (Figure 6b).Interestingly, our observation that Akt phosphorylation augments its histone acetylationfunction is in agreement with a recent study showing the requirement for Akt in modulatinghistone acetylation status in tumor cells exhibiting metabolic defects [39].