In regards to T2D management, clinical guidelines recommend carbohydrate intake from high-fiber foods such as vegetables, fruit, legumes and whole grains, while limiting SFAs intake and promoting that of MUFAs and omega-3 PUFAs [149, 150], all of which have been associated to different extents with an increased GLP-1 secretion. Here, GLP1R is linked to type 2 diabetes mellitus.