Of particular note, BRD4 promotes the expression of Col1A1, which encodes Type I collagen, in response to exogenous TGF-β, thereby leading to both lung and liver fibrosis (Friedman, 2008; Mederacke et al., 2013; Tang et al., 2013; Ding et al., 2015). The gene discussed is BRD4; the disease is Hepatic fibrosis.