Expression of BCL-2 was weaker in tissues treated with NC-shRNA + DDP (Fig. 7C and D), and the greatest effect was observed in the group treated with ST6Gal-I-shRNA + DDP (Fig. 7E and 7F), suggesting that the presence of ST6Gal-I-shRNA increased apoptosis effect in HeLa cells and enhanced the effect of DDP on the inhibition of tumor growth. The gene discussed is ST6GAL1; the disease is neoplasm.