In this context, changes observed in this paper to IL-6 could be considered not only to support considerations surrounding neuroinflammation in autism, but also to supportits potentialas a peripheral marker in the interpretation of clinical findings related to comorbidities in autism, with the particular suggestion of considering the frontal localization of epileptic focus, since the frontal pathology is prominent in autism [56]. The gene discussed is IL6; the disease is autism.