Enriched pathway analysis of Cd/E2/NRF1 common genes revealed the top pathways that included: (1) Metabolism (26 genes); (2) Gene Expression (25 genes); (3) Disease (24 genes); (4) Signal Transduction (21 genes); (5) Metabolic pathways (20 genes); (6) Immune System (18 genes); (7) Cell Cycle (17 genes); (8) Cancer Pathways (15 genes); (9) Developmental Biology (15 genes) and (10) Metabolism of proteins (12 genes) (Table 4). Here, NRF1 is linked to cancer.