ABCC2 and breast cancer: The fluorescent dye 5-chloromethylfluorescein diacetate (CMFDA), which binds the apical transporter multidrug resistance-associated protein 2 (MRP2), enabled real-time imaging of BC structures in differentiated HepaRG (Fig. 3a) and HepG2 cells, and allowed us to measure the effect of cytokines on tight junction integrity [5].