Madsen et al. (23) observed that the homozygousgenotype encoding MBL2 deficiency could be considered a risk factor forearly onset of atherosclerosis or, sometimes, a more intense progression of the disease.It was observed that functionally deficient MBL2 variants wereassociated with a doubled risk of myocardial infarction and an increase inatherosclerosis (28). The gene discussed is MBL2; the disease is myocardial infarction.