Multivariable linear regression analysis further demonstrated an independent correlation between IL-34 and eGFR (β = −0.152, p = 0.001) and log cystatin C (β = 0.118, p = 0.006), respectively, after adjusting for age, gender, body mass index (BMI), hypertension, diabetes, hemoglobin, albumin, high sensitivity C reactive protein (hsCRP) and NT-proBNP (Table 2). The gene discussed is CST3; the disease is Hypertension.