To define the importance of MC expression of TNFRSF14 in vivo, we induced our model of asthma in genetically MC-deficient KitW-sh/W-sh mice engrafted intravenously (i.v.)with Tnfrsf14+/+ or Tnfrsf14−/− BMCMCs. This evidence concerns the gene TNFRSF14 and asthma.