Further evidence supporting the stem cell-like properties of GALNT14-expressing BCCs include: (1) GALNT14 induces SOX4 expression, which subsequently increases transcription of stem cell-associated factors SOX2 and OCT4; and (2) GALNT14 augments mammary tumour initiation when a limited number of BCCs are implanted. The gene discussed is POU5F1; the disease is breast cancer.