We also previously showed that in patients with type 2 diabetes, physiological correlations between heat shock protein 70 (HSPA1A) and plasminogen activator inhibitor-1 disappear [17] and pathological correlations between heat shock protein 70 and asymmetric dimethylarginine and also leptin and HSP70 emerge [14, 16]. This evidence concerns the gene HSPA1A and type 2 diabetes mellitus.