There have been studies showing that suppression the phosphorylation of VEGFR‐2 led to inhibition of cancer cell migration and metastasis.47, 48 The prosurvival activity of phosphoinositide 3 kinase (PI3K)/Akt pathway has been identified that actively engages with the migratory process in motile cells, including metastatic cancer cells. This evidence concerns the gene AKT1 and cancer.