IGHE and asthma: We had two main goals in this work: (1) to determine whether WGP could accurately predict several asthma‐related phenotypes (pre‐ and post‐bronchodilator FEV1, airway hyper responsiveness, serum IgE, eosinophils, longitudinal lung function growth patterns [reduced growth and/or early decline vs. normal] and steroid responsiveness); and (2) to compare different WGP methodologies to identify the most powerful and accurate methods for prediction of asthma‐related phenotypes.