CD4 and lymphoma: To determine whether Hsp90 inhibition by DMAG would also protect from aGvHD induced by total CD4+ and CD8+ T cells and to assess its impact on the GvT effect, we inoculated BALB/c mice with BCL1 lymphoma cells followed by transplantation of either TCD BM cells only or TCD BM cells together with 5 × 105 (Fig. 3A, C) or 5 × 104 T cells/mouse (Fig. 3B, C).