This lncRNA is located near the melanoma-specific oncogene MITF and is always included in genomic amplifications involving MITF. Even in melanomas with no genomic amplification of this locus, SAMMSON is expressed in most cases, increases growth and invasiveness and is a target for SOX10 [161], a key TF in melanocyte development which is deregulated in melanoma [162]. This evidence concerns the gene MITF and melanoma.