CASP3 and neuroblastoma: In an earlier study, Janhom and Dharmasaroja, suggested the inhibition effect of α-MG against MPP+-induced apoptosis in neuroblastoma SH-SY5Y cells may be associated with the reduction of ROS production, modulation of the balance of pro- and anti-apoptotic genes, and suppression of caspase-3 activation [23].