Also in T2D patients, TLR8 gene expression correlated positively with CD68 (r = 0.61, P < 0.0001) (Fig. 4e), CD11c (r = 0.52, P = 0.0002) (Fig. 4f), CD86 (r = 0.77, P < 0.0001) (Fig. 4g), and CD163 (r = 0.72, P < 0.0001) (Fig. 4h). Here, ITGAX is linked to type 2 diabetes mellitus.