In addition, some risk factors have been identified, such as systemic inflammatory response syndrome (SIRS), sepsis, multiple organ failure (MOF), age, gender, mechanical ventilation, morbidity, renal failure, hypotension, hyperosmolarity, parenteral nutrition, low serum albumin, immobilization, medication and hypoxia [2, 7–9]. The gene discussed is ALB; the disease is systemic inflammatory response syndrome.