As shown in Table 1, increased expression of Derlin-1 was significantly correlated with tumor stage (P < 0.005), histological grade (P < 0.001), and lymph node metastasis (P < 0.001), but not with the patient age (P = 0.758) and gender (P = 0.831). This evidence concerns the gene DERL1 and metastatic malignant neoplasm in the lymph nodes.