However, further in-depth studies are necessary to explore the role of Derlin-1 in tumor invasion and metastasis and in other aspects of bladder cancer progression, as well as to elucidate the molecular mechanisms underlying the involvement of Derlin-1 in these processes, which may broaden our knowledge regarding Derlin-1 as an oncogene and as a potential therapeutic target for bladder cancer. This evidence concerns the gene DERL1 and neoplasm.