Our study was not designed to directly investigate the genetics of susceptibility to ascariasis, but, considering the biological role of chitinases and chitinase-like proteins in the context of Th2-mediated inflammation and the predicted functional effect of the detected variants (e. g. rs880633 Arg145Gly), our findings suggest that they are relevant in the regulation of the intensity of the specific IgE response to ABA-1, which is potentially important information for understanding the genetic susceptibility to ascariasis. The gene discussed is IGHE; the disease is ascariasis.