We utilized melanoma cells lines lacking detectable mutations in PERK, but expressing the following Braf alleles: BrafWT or BrafV600E/D (1205 Lu, 451LU, WM983B, WM35, WM3918, WM239A, WM3211, WM1791C, C8161 (http://www.wistar.org/lab/meenhard-herlyn-dvm-dsc/page/melanoma-cell-lines-0). Here, EIF2AK3 is linked to melanoma.