To further confirm whether FOXO4 was directly involved in the pro-metastatic effect mediated by miR-150 in NSCLC, miR-150 inhibitor and FOXO4 siRNA were co-transfected into H460 and A549 cells to simultaneously silence miR-150 and FOXO4 expression. Here, FOXO4 is linked to non-small cell lung carcinoma.