Thus, to identify whether LRRK2 may be a factor contributing to the degeneration of dopamine neurons in PINK1-PD, we made iPSC lines from the two PINK1-exon7/del patients (PDP1 and PDP3 lines) and one carrier (PDP2) (Supplementary Fig. S2 and Fig. 4a, b). This evidence concerns the gene PINK1 and Parkinson disease.