Post hoc analysis of the NLRP3 gene showed 6.55-fold (p = 0.006) and 11.30-fold (p = 0.010) upregulation in the CKDu and CKD groups, respectively, whereas FGF23 showed a similar pattern with 21.91-fold (p = 0.003) and 134.97-fold (p = 0.001) upregulation in the CKDu and CKD groups. This evidence concerns the gene NLRP3 and chronic kidney disease.