Ipilimumab, an anti-CTLA-4 antibody, is being tested in two clinical trials that enroll patients with cervical cancer; an OX40 immune modulator is being tested in combination with tremelimumab, an anti-CTLA-4 antibody; Urelumab-an anti-4-1BB/ CD137 antibody and nivolumab, an anti-PD-1 antibody; Lirilumab - an anti-KIR antibody, is being tested in combination with nivolumab; an anti-GITR antibody is also tested. The gene discussed is CTLA4; the disease is cervical carcinoma.