This extensive analysis revealed that the BD ≥ 4 group exhibited statistically significantly higher circulating levels of multiple innate-derived (IL-1RA, IL-6, IL-8/CCL8, MCP-1/CCL2, IFN-α, MIP-1β/CCL4, and TNF-α; see Supplementary Figure  S1 of the Supplementary Material available online at http://dx.doi.org/10.1155/2016/7950374) and lymphoid-derived (IL-7, IL-4, IFN-γ, IL-2, IL-13, IL-5, and sIL-2Rα; Supplementary Figure  S2) inflammatory mediators when compared to the BD < 4 group. This evidence concerns the gene CXCL8 and Behcet disease.