The affinity of type 1 cells for CAH is further evidence that they are peptidergic: the peptidergic neurons of other phyla are stained by CAH due to its affinity for the sulphydryl groups of the cysteine-rich carrier proteins, or neurophysins [78,80], that facilitate the packaging of peptides into, and their secretion from, DCVs [81]. This evidence concerns the gene PROS1 and congenital adrenal hyperplasia.